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This thesis sheds lights on collaborations and transfer of knowledge between Jewish and Christian scholars in France during the 13th and 14th centuries. We propose a comparative analysis of different exchanges, in three distinct areas: theological, philosophical and astronomical. Taking into account the Latin and Hebrew sources that testify this transmission of knowledge, we propose an in-depth study, dividing in two sections. The first part narrates the evolution of education in the Jewish communities and in Christian society. The second part analyses the context of the Extractiones de Talmut, the transmission of knowledge between Maimonides and Thomas Aquinas, the close collaboration between Jacob ben Makhir and Armengaud Blaise, as well as the significant intellectual exchange between Gersonides and his fellow Christians. Our objective is to answer the following questions: did Christian and Jewish scholars receive information according to their own intellectual value, ignoring their source? And was there a direct influence from one scholar towards the other? Thus, this study demonstrates the different motives of these exchanges through a contextual field constituted by a specific intellectual event. We will perceive that these relations vacillate between mistrust and admiration.